Joshi LB Acta Med Leg Soc (Liege) 1983;33(1):1075-8. Potassium thiocyanate was used over 50 years ago for the treatment of hypertension and its toxicity appears to cause a neurological disorder consisting of generalized weakness, Potassium Thiocyanate, 0.1M Created by Global Safety Management, Inc. -Tel: 1-813-435-5161 - www.gsmsds.com CAS 333-20-0 Potassium Thiocyanate, ACS 0.9718 % CAS 7732-18-5 Deionized Water 99.028 % Percentages are by weight SECTION 4 : First aid measures Description of first aid measures After inhalation: Remove to fresh air. High purity, submicron and nanopowder forms may be considered. Poisoning with ethyl alcohol and potassium thiocyanate. Chemical Properties Potassium thiocyanate, KSCN,also known as potassium sulfocyanate and potassium rhodanide, is a colorless deliquescent crystalline solid that melts at 173°C (343 OF) and decomposes at 500°C(932 OF). Toxic effects include skin eruptions, psychosis, and collapse; [Merck Index] May cause CNS effects (excitement and convulsions); Prolonged or repeated exposure may cause thyroid and CNS effects leading to impaired function and hypothyroidism; [ICSC] Human ingestion of 80 mg/kg causes hallucinations, convulsions, and muscle weakness; Human ingestion of 428 mg/kg causes toxic … Use: Potassium Thiocyanate is generally immediately available in most volumes. 12.1 Toxicity Toxicity to fish LC50 - Oncorhynchus mykiss (rainbow trout) - > 100 mg/l - 96.0 h Toxicity to daphnia and other aquatic invertebrates EC50 - Daphnia magna (Water flea) - 11 mg/l - 48 h 12.2 Persistence and degradability no data available 12.3 Bioaccumulative potential Toxicity of different thiocyanate compounds other than guanidine thiocyanate has been described [1-3]. Acute 96‐h static bioassays were conducted with juvenile rainbow trout (Salmo gairdneri) to assess the toxicity of thiocyanate (CNS) and cyanate (CNO), as potassium salts, under several pH and temperature regimes.Bioassays were conducted at pH 6 or 8 and at temperatures of 5 or 12°C. Reproductive toxicity No data available 11.4 Toxicological information Potassium Thiocyanate Oral Rat LD50 (mg/kg): 854 Section 12: Ecological information 12.1 Toxicity: Toxicity to daphnia and other aquatic vertebrates Potassium Thiocyanate EC50 Daphnia magna (Water flea) (mg/l - 48hr): 11 Section 13: Disposal considerations reports of guanidine thiocyanate toxicity from oral ingestion. The short answer is “no”, as cyanide poisoning takes place when the cyanide ion binds to iron preventing oxygen uptake by the body's cells. Also asked, can potassium thiocyanate kill you? Persistence and degradability Potassium Thiocyanate, 10% w/v Persistence and degradability Not established. antonio del solar v, gaston dussaillant g, moisÉs brodsky b, guillermo rodrÍguez c. fatal poisoning from potassium thiocyanate used in treatment of hypertension: report of a case and review of the literature. Soluble in water and alcohol,it has no odor and a saline taste. Toxicity Potassium Thiocyanate (333-20-0) LC50 fish 1 > 100 mg/l EC50 Daphnia 1 11 mg/l 12.2. Potassium thiocyanate is a potassium salt which is the monopotassium salt of thiocyanic acid. PMID: 6613628. Observations on thyroid function in hypertensive patients treated with potassium thiocyanate. To describe fatal herbicide poisoning with Radoxone TL composed of aminotriazole and ammonium thiocyanate.
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